MEDICAL DESCRIPTION OF HCQS TABLET:
HCQS Tablet contains Hydroxychloroquine (200mg) an antimalarial and Immunosuppressant agent used to treat malaria, malaria prophylaxis, Rheumatoid arthritis, and Systemic lupus erythematosus. It produces its action by killing the organism which is responsible for infection and it also decreases the effect of the immune system in rheumatoid arthritis, and systemic lupus erythematosus.
USE OF HCQS TABLET (Indication of Hydroxychloroquine):
It is used in the treatment of malaria, malaria prophylaxis, Rheumatoid arthritis, and Systemic lupus erythematosus.
HCQS TABLET BENEFITS:
Malaria:
It is a parasitic infection usually spread from mosquitoes to humans. It is caused by the Plasmodium parasite. Symptoms include fever, headache, sweating, nausea, vomiting, weakness, and an enlarged liver.
Rheumatoid arthritis:
It is a chronic inflammatory disorder that usually occurs when our immune system attacks our healthy body tissues instead of foreign invaders. Symptoms include fever, dry eyes, chest pain, weight loss, loss of appetite, joint pain and tiredness
Systemic Lupus Erythematosus:
It is an autoimmune disease where our immune system attacks our body. Symptoms include joint pain, anemia, rash, severe fatigue, hair loss, and blood clotting problems.
HOW THE HCQS TABLET WORKS:
HCQS tablets contain Hydroxychloroquine (200mg) is an antimalarial agent that produces its action by inhibiting the polymerization of heme and it also inhibits the enzymes by interacting with parasitic DNA. For Rheumatoid arthritis and Systemic lupus erythematosus it produces its action by inhibiting the overactivity of the immune system which is responsible for inflammation and joint pain.
CONTRAINDICATION OF HCQS TABLET:
If you are allergic to hydroxychloroquine and its combinations, it is advisable not to consume the medicine. It is contraindicated to use this medicine in patients with a history of liver diseases because it may worsen their condition
HCQS TABLET SIDE EFFECT
Stomach pain
Cardiomyopathy
Nausea
Vomiting
Diarrhea
Abnormal liver function
Rash
Headache
Dizziness
Depression
Hair loss
FAQ OF HCQS TABLET
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Is HCQS tablet habit forming?
No, this medicine does not show any habit-forming tendencies.
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How long does it take for the HCQS tablet to start working?
It may take a few weeks or months to show an improvement in rheumatoid arthritis. But take the medicine regularly.
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Is HCQS tablet available in over-the-counter medication?
No, this medicine is not available as over-the-counter. It should be taken only if it is prescribed by your doctor.
PRECAUTIONS AND GENERAL WARNING OF HCQS TABLET
ALCOHOL:
While taking hydroxychloroquine medicine it is crucial to consume the alcohol. For more details visit the doctor or nearby hospital for a consultation
DRIVING OR OPERATING MACHINERY
It is advice not to drive vehicles or operate the machine while you taking the hydroxychloroquine sulphate medicine,it is consider to be unsafe. For more details visit the doctor or nearby hospital for a consultation
PREGNANCY:
As per the available data’s it is consider to be a safe drug can be use during the pregnancy and does not produce unwanted effects on the fetus. For more details visit the doctor or nearby hospital for a consultation.
BREASTFEEDING:
It is considered safe to use this medicine during breastfeeding it does not produce harmful effects on the fetus. For more details visit the doctor or nearby hospital for a consultation
KIDNEY PROBLEM:
This medicine should be administered with caution in patients with kidney diseases. Adjust the dose if needed. For more details visit the doctor or nearby hospital for a consultation
LIVER PROBLEM:
This medicine should be administered with caution in patients with liver diseases. Adjust the dose if needed. For more details visit the doctor or nearby hospital for a consultation
HOW TO TAKE A HCQS TABLET:
Hydroxychloroquine gives better results when you take the medicine with food, take the tablet fully, and do not chew or crush the tablet. Take the tablets as per the dose prescribed by the doctor. Do not take extra doses and dosage of the medicine, it may lead to undesired and unwanted effects.
USE OF HCQS TABLET IN ADULTS:
If the medicine is prescribed by the doctor, then it is advised to consume the medicine as per the doctor’s prescription of dose and dosage, For more details visit the doctor for the consultation.
USE OF HCQS TABLET IN CHILDREN:
If the medicine is prescribed by the doctor, then it is advised to consume the medicine as per the doctor’s prescription of dose and dosage, For more details visit the doctor for consultation.
USE OF HCQS TABLETS IN ELDERLY PATIENTS:
HCQS tablets should be used with caution in patients in an elderly age group, which leads to developing further medical problems and worsening the patient’s health conditions. Kindly consult with your doctor. Dose adjustment is required for the patient based on the medical condition and previous medical history of the patient.
OTHER GENERAL WARNINGS:
Patients with a history of psoriasis, severe hypoglycemia, liver diseases, and glucose-6-phosphate dehydrogenase deficiency need to consult the doctor before consuming the medicine and caution to be taken while taking the medicine
GENERAL INSTRUCTIONS:
HCQS Tablet contains Hydroxychloroquine (200mg) is an antimalarial and Immunosuppressant agent used to treat malaria, malaria prophylaxis, Rheumatoid arthritis, Systemic lupus erythematosus, Coronavirus Disease (off label), and Porphyria cutanea tarda (off-label). It produces its action by killing the organism which is responsible for infection and it also decreases the effect of the immune system in rheumatoid arthritis, and systemic lupus erythematosus.
Inform the doctor, if you have the following complications earlier,
If you have a medical history of GI tract disease
If you have an immunodeficiency disease like the Human Immunodeficiency Virus (HIV) /Acquired immunodeficiency syndrome (AIDS).
If you have allergic conditions like itching and rashes
If you are planning to become pregnant or currently under the breastfeed
If you are suffering from diarrhea, stomach pain, etc
DRUG INTERACTION WITH HCQS TABLET
Following drugs increases the effect of hydroxychloroquine
Hydroxychloroquine will decrease the effect of the rabies vaccine by pharmacodynamic antagonism.
Adalimumab and hydroxychloroquine increase the risk of infection.
Amiodarone and hydroxychloroquine increase the QTc intervals
Hydroxychloroquine will increase the effect of cyclosporine by the P-glycoprotein efflux transporter.
Hydroxychloroquine will increase the effect of insulin aspart by increasing the hypoglycaemic risk
Grapefruit may increase the blood levels and effect of hydroxychloroquine which results in irregular heart rate.
OVERDOSE
Consume the medicine as per the doctor’s advice and prescribed dose and dosage. Avoid taking any extra dose of medicine then original prescribed dose.Do not overdose for the immediate effect,which leads to undesired effects. If you have taken the overdose/extra dose of the medicine immediately visit the doctor or nearby hospital for medical consultation.
MISSED DOSE
Take the medicine as per the prescription of doctor.
Take only dose and dosage prescribed by the doctor and doctor advice.
Do not take the missed or forgot dose to adjust the dose,if you missed the dose skip the missed dose continue the regular schedule dose medicine.
Consuming the medicine for two time to compensate the missed or forgot dose should be avoid.
Conditions of Storage:
Store the medicine at 30°c at room temperature.
Keep reaching out to children and pets, to avoid the risk of swallowing.
Protect from sunlight and heat
Quick recall:
HCQS tablets have an active ingredient called Hydroxychloroquine (200mg)
It is an antimalarial and Immunosuppressant agent used to treat malaria, malaria prophylaxis, Rheumatoid arthritis, Systemic lupus erythematosus
Take this medicine with food
Kindly do eye tests while you are receiving this medicine
Inform to your doctor if you have any previous medical problems like headache, fever, stomach pain, vomiting, etc.
To know about your disease status, your doctor may ask for a routine checkup of your stools and blood samples in the middle of the treatment.to check whether the infection level is reduced or not.
If you are taking antacids take the medicine before 4 hours or after 4 hours.
REFERENCES:
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 669-71.
Hydroxychloroquine sulfate [Prescribing Information]. Ahmedabad, Gujarat: Amneal Pharmaceuticals Pvt. Ltd.; 2023. [Accessed 03 Jul. 2023]. (online) Available from: https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=7804f5d2-41a6-4523-a277-6967e984e88e&type=display#
Hydroxychloroquine sulfate. St. Michael, Barbados: Concordia Pharmaceuticals Inc.; 2017. [Accessed 17 Jun. 2019] (online) Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/009768s037s045s047lbl.pdf
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